The SET 7/9 antibody (clone s4E5) from MyBioSource.com is a Mouse Monoclonal antibody to KMT7, SET9, and SETD7. This antibody recognizes Human antigen. The SET 7/9 antibody (clone s4E5) has been validated for the following applications: ELISA, and Western Blot.
Description
Set7/9 is a histone methyltransferase(HMTase) that transfers methyl group to Lys4 of histone H3, in complex with S-adenosyl-L-methionine(AdoMet). The methylation of lysine residues of histones plays a critical role in the regulation of chromatin structure and gene expression. Acetylation, phosphorylation and methylation of the amino-terminal tails of histone are thought to be involved in the regulation of chromatin structure and function. The enzymes identified in the methylation of specific lysine residue on histones belong to the SET family with just one exception. Set7/9, unlike most other SET proteins, is exclusively a mono-methylase